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Clinically Confirmed Stroke with Negative Diffusion-Weighted Imaging Magnetic Resonance Imaging Stroke 46:3142-3148, Makin, S.D.J.,et al, 2015 See this aricle in Pubmed Article Abstract Nearly one third of patients with nondisabling stroke do not have a relevant lesion on acute DWI-MRI. Patients with negative DWI-MRI had no better prognosis than patients with a lesion. DWI-negative stroke patients should receive secondary prevention.

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